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Tag: sun2

SUN2 Modulates HIV-1 Infection and Latency through Association with Lamin A/C To Maintain the Repressive Chromatin

Posted on May 9, 2018 by Emilie Chabot

  In this study,  researchers  performed in-depth virological and cell biological studies and discovered that an inner nuclear membrane protein, SUN2, is a novel chromatin reassembly factor that maintains repressive chromatin and thus modulates HIV-1 transcription and latency. Targeting SUN2 may lead to new strategies for an HIV cure. The well-cited Bioruptor was used to[…]

Posted in Chromatin Tagged chromatin shearing, lamin, sun2 Leave a comment

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